منابع مشابه
Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions
Elevated incidences of Amyotrophic Lateral Sclerosis/Parkinsonism Dementia complex (ALS/PDC) is associated with β-methylamino-L-alanine (BMAA), a non-protein amino acid. In particular, the native Chamorro people living in the island of Guam were exposed to BMAA by consuming a diet based on the cycad seeds. Carbamylated forms of BMAA are glutamate analogues. The mechanism of neurotoxicity of the...
متن کاملMethyl N-(dimethoxyphosphoryl)carbamate
In the title compound, CH3OC(O)NHP(O)(OCH3)2, the P atom has a slightly distorted tetra-hedral configuration. The mixed imide moiety can be described as cisoid-transoid in which the two opposing dipoles (P=O and C=O) are oriented with a O=C⋯P=O torsion angle of 150.88(18)°. In the crystal, molecules are linked by pairs of N-H⋯O hydrogen bonds, forming inversion dimers.
متن کاملOrganophosphate and carbamate poisoning.
Organophosphates (OPs) and carbamates have a wide variety of applications, most commonly as pesticides used to eradicate agricultural pests or control populations of disease-carrying vectors. Some OP and carbamates have therapeutic indications such as physostigmine. Certain organophosphorus compounds, known as nerve agents, have been employed in chemical warfare and terrorism incidents. Both cl...
متن کاملDetection of carbamate as a product of the carbamate kinase-catalyzed reaction by stopped flow spectrophotometry.
It has been commonly assumed that carbamate kinnse (EC 2.7.2.2, ATP : carbamate phospllotransferase) catalyzes the transfer of a phosphate group between 1TP and the carbamate ion. Evidence which has been put forward supporting this belief is the observation that freshly dissolved ammonium carbamate is a much better substrate for the enzyme than freshly dissolved ammonium carbonate at pH 9.4 (1)...
متن کاملMethyl N-(4-chlorophenyl)carbamate
In the title compound, C(8)H(8)ClNO(2), the dihedral angle between the chloro-benzene ring and the side chain is 8.79 (11)°. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into a C(4) chain propagating in the b-axis direction.
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1937
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)74545-6